Endoform™ Antimicrobial and Endoform™ Natural Restorative Bioscaffold products work in all phases of healing to stabilize, correct, build and organize tissue.

Endoform™ products are made from AROA ECM™ technology and contain more than 150 extracellular matrix (ECM) proteins that enable it to interact with patient’s cells throughout all phases of healing.^{(1, 2)} Endoform™ products are 85% collagen and 15% important secondary molecules, including structural and adhesion proteins, and glycosaminoglycans (GAGs).⁽¹⁾ Endoform™ products only contain components found in tissue extracellular matrix.

During the inflammatory phase, chronic wounds are characterized by elevated wound proteases that limit healing by digesting important dermal proteins.⁽³⁾ Endoform™ products can help indicate the presence or absence of proteases and restores protease balance.^{(4, 5)}  If Endoform™ products are not visible in the wound bed at the time of reapplication, this can indicate elevated wound protease activity. However, if Endoform™ is visible, this can indicate that protease balance has been restored.

Endoform™ products also contain residual vascular channels that facilitate the rapid establishment of a dense capillary network by supporting migrating endothelial cells to establish new vasculature and a robust blood supply to help build new tissue.⁽⁶⁾ This process is termed angioconduction.